WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for each enriched gene sets are listed in this table.
For each gene set, the first row lists database name, gene set name , and corresponding gene set ID.
The second row lists the following statistics:
Finally, genes in the pathway are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:KEGG pathway       Name:Focal adhesion       ID:04510
C=200; O=5; E=0.21; R=23.44; rawP=2.40e-06; adjP=2.16e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000112769 NA LAMA4 laminin, alpha 4 3910 ENSG00000112769
2  ENSG00000213949 NA ITGA1 integrin, alpha 1 3672 ENSG00000213949
3  ENSG00000037280 NA FLT4 fms-related tyrosine kinase 4 2324 ENSG00000037280
4  ENSG00000091409 NA ITGA6 integrin, alpha 6 3655 ENSG00000091409
5  ENSG00000196878 NA LAMB3 laminin, beta 3 3914 ENSG00000196878


Database:KEGG pathway       Name:ECM-receptor interaction       ID:04512
C=85; O=4; E=0.09; R=44.12; rawP=2.15e-06; adjP=2.16e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000112769 NA LAMA4 laminin, alpha 4 3910 ENSG00000112769
2  ENSG00000213949 NA ITGA1 integrin, alpha 1 3672 ENSG00000213949
3  ENSG00000091409 NA ITGA6 integrin, alpha 6 3655 ENSG00000091409
4  ENSG00000196878 NA LAMB3 laminin, beta 3 3914 ENSG00000196878


Database:KEGG pathway       Name:Small cell lung cancer       ID:05222
C=85; O=3; E=0.09; R=33.09; rawP=0.0001; adjP=0.0004
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000112769 NA LAMA4 laminin, alpha 4 3910 ENSG00000112769
2  ENSG00000091409 NA ITGA6 integrin, alpha 6 3655 ENSG00000091409
3  ENSG00000196878 NA LAMB3 laminin, beta 3 3914 ENSG00000196878


Database:KEGG pathway       Name:Hematopoietic cell lineage       ID:04640
C=88; O=3; E=0.09; R=31.96; rawP=0.0001; adjP=0.0004
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000213949 NA ITGA1 integrin, alpha 1 3672 ENSG00000213949
2  ENSG00000157404 NA KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 3815 ENSG00000157404
3  ENSG00000091409 NA ITGA6 integrin, alpha 6 3655 ENSG00000091409


Database:KEGG pathway       Name:Amoebiasis       ID:05146
C=106; O=3; E=0.11; R=26.53; rawP=0.0002; adjP=0.0007
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000112769 NA LAMA4 laminin, alpha 4 3910 ENSG00000112769
2  ENSG00000182621 NA PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 23236 ENSG00000182621
3  ENSG00000196878 NA LAMB3 laminin, beta 3 3914 ENSG00000196878


Database:KEGG pathway       Name:Toxoplasmosis       ID:05145
C=132; O=3; E=0.14; R=21.31; rawP=0.0004; adjP=0.0010
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000112769 NA LAMA4 laminin, alpha 4 3910 ENSG00000112769
2  ENSG00000091409 NA ITGA6 integrin, alpha 6 3655 ENSG00000091409
3  ENSG00000196878 NA LAMB3 laminin, beta 3 3914 ENSG00000196878


Database:KEGG pathway       Name:Pathways in cancer       ID:05200
C=326; O=4; E=0.35; R=11.50; rawP=0.0004; adjP=0.0010
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000112769 NA LAMA4 laminin, alpha 4 3910 ENSG00000112769
2  ENSG00000157404 NA KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 3815 ENSG00000157404
3  ENSG00000091409 NA ITGA6 integrin, alpha 6 3655 ENSG00000091409
4  ENSG00000196878 NA LAMB3 laminin, beta 3 3914 ENSG00000196878


Database:KEGG pathway       Name:African trypanosomiasis       ID:05143
C=35; O=2; E=0.04; R=53.57; rawP=0.0006; adjP=0.0014
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000112769 NA LAMA4 laminin, alpha 4 3910 ENSG00000112769
2  ENSG00000182621 NA PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 23236 ENSG00000182621


Database:KEGG pathway       Name:Cytokine-cytokine receptor interaction       ID:04060
C=265; O=3; E=0.28; R=10.61; rawP=0.0029; adjP=0.0052
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000186827 NA TNFRSF4 tumor necrosis factor receptor superfamily, member 4 7293 ENSG00000186827
2  ENSG00000157404 NA KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 3815 ENSG00000157404
3  ENSG00000037280 NA FLT4 fms-related tyrosine kinase 4 2324 ENSG00000037280


Database:KEGG pathway       Name:Arrhythmogenic right ventricular cardiomyopathy (ARVC)       ID:05412
C=74; O=2; E=0.08; R=25.34; rawP=0.0029; adjP=0.0052
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000213949 NA ITGA1 integrin, alpha 1 3672 ENSG00000213949
2  ENSG00000091409 NA ITGA6 integrin, alpha 6 3655 ENSG00000091409




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).